Synthesis and evaluation of 1-deoxy-D-xylulose 5-phosphoric acid analogues as alternate substrates for methylerythritol phosphate synthase

DOI: 10.1021/jo048022h

Source and publish data:

Journal of Organic Chemistry p. 1978 - 1985 (2005)

Update date:2022-09-26

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Authors:

Fox, David T.

Poulter, C. Dale

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Article abstract of DOI:10.1021/jo048022h

(Chemical Equation Presented) Four deoxyxylulose phosphate (DXP) analogues were synthesized and evaluated as substrates/ inhibitors for methylerythritol phosphate (MEP) synthase. In analogues CF₃-DXP (1), CF ₂-DXP (2), and CF-DXP (3)

Full text of DOI:10.1021/jo048022h

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