ONE-POT SYNTHESIS OF KETONES FROM CARBOXYLIC ACIDS AND GRIGNARD REAGENTS USING N,N-DIPHENYL-p-METHOXYPHENYLCHLOROMETHYLENIMINIUM CHLORIDE

Article abstract of DOI:10.1016/S0040-4039(00)85572-0

N,N-Diphenyl-p-methoxyphenylchloromethyleniminium chloride is found to be an effective condensation reagent of carboxylic acids and Grignard reagents under mild conditions to afford the corresponding ketones in high yields.