Tandem addition/cyclization of alkynylzinc reagents to enantiopure 2-tert-butyl-3,5-dimethyl-2,3-dihydroimidazol-4-one N-oxide: Potential precursors of quaternary α-amino acids

DOI: 10.1002/ejoc.200400861

Source and publish data:

European Journal of Organic Chemistry p. 2694 - 2701 (2005)

Update date:2022-07-29

Topics:

Authors:

Cantagrel, Fredaric

Pinet, Sandra

Gimbert, Yves

Chavant, Pierre Y.

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Article abstract of DOI:10.1002/ejoc.200400861

A new enantiopure cyclic nitrone, a potential electrophilic alanine synthon, has been prepared. Its reaction with alkynylzinc reagents led to a tandem addition/cyclization reaction with complete regio- and stereoselectivity. The adducts are potential prec

Full text of DOI:10.1002/ejoc.200400861

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