Stereoselective synthesis of cytotoxic anhydrophytosphingosine pachastrissamine (Jaspine B) from D-xylose

DOI: 10.1021/jo051644y

Source and publish data:

Journal of Organic Chemistry p. 1251 - 1253 (2006)

Update date:2022-08-04

Topics:

Authors:

Du, Yuguo

Liu, Jun

Linhardt, Robert J.

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Article abstract of DOI:10.1021/jo051644y

The first naturally occurring anhydrophytosphingosine, pachastrissamine (jaspine B), a marine compound cytotoxic toward P388, A549, HT29, and MEL28 cell lines at IC₅₀ = 0.01 μg/mL level, has been stereoselectively synthesized from D-xylose in 1

Full text of DOI:10.1021/jo051644y

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Product name:2,5-anhydro-3-O-benzyl-D-xylose diethyl acetal

Cas No:876917-09-8

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