Biological activity and a modified synthesis of 8-amino-3-β-D-ribofuranosyl-1,2,4-triazolo[4,3-a]pyrazine, an isomer of formycin

Article abstract of DOI:10.1021/jm00373a020

A two-step synthesis of 8-amino-3-β-D-ribofuranosyl-1,2,4-triazolo[4,3-a]pyrazine (3), which is an isomer of formycin that resembles 3-deazaadenosine, is reported. Compound 3 is also described as being a very poor substrate for adenosine deaminase and bot