Welcome to LookChem.com Sign In|Join Free
  • or

378-44-9

Post Buying Request

378-44-9 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
Factory supply 99% Betamethasone powder in stock with fast and safe shipping
Cas No: 378-44-9
No Data 1 Kilogram 1 Metric Ton/Month Shaanxi Mingqi Chemical Co., Ltd Contact Supplier
Betamethasone Manufacturer
Cas No: 378-44-9
No Data 100 Gram Metric Ton/Day Wuhan Zenuo Biological Medicine Technology Co Ltd Contact Supplier
High Quality Betamethasone / Celestone Powder
Cas No: 378-44-9
USD $ 0.1-0.2 / Kilogram 1 Kilogram 1000 Kilogram/Month Binbo Biological Co., Ltd Contact Supplier
Betamethasone CAS Rn 378-44-9
Cas No: 378-44-9
USD $ 1950.0-2000.0 / Kilogram 1 Kilogram 200 Kilogram/Month Wuhan Jing Chu Chen Pharmaceutical Chemical Co., Ltd. Contact Supplier
Betamethasone USP EP CAS 378-44-9
Cas No: 378-44-9
USD $ 10.0-10.0 / Kilogram 1 Kilogram 100 Kilogram/Month Antimex Chemical Limied Contact Supplier
Betamethasone Anti - Inflammatory Prohormones Steroids Betamethasone Hormone
Cas No: 378-44-9
No Data 10 Gram 10000 Metric Ton/Month Hubei XinRunde Chemical Co., Ltd Contact Supplier
Betamethasone
Cas No: 378-44-9
No Data No Data No Data ZHEJIANG SA-CHEN (sachen)PHARMACEUTICAL TECHNOLOGY COMPANY Contact Supplier
Betamethasone Manufacturer/High quality/Best price/In stock
Cas No: 378-44-9
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
Betamethasone CAS NO.378-44-9
Cas No: 378-44-9
USD $ 1.0-3.0 / Metric Ton 1 Metric Ton 10 Metric Ton/Day Hebei yanxi chemical co.,LTD. Contact Supplier
Betamethasone with best price and top quality
Cas No: 378-44-9
USD $ 800.0-1000.0 / Kilogram 1 Kilogram 5000 Kilogram/Month Kono Chem Co.,Ltd Contact Supplier

378-44-9 Usage

production method

According to U.S. Patent No. 3,164,618, betamethasone acetate is dealt with hydrochloric acid in methanol-chloroform-water mixture , it can be converted to betamethasone.

Toxicity grading

Middle toxic

Chemical Properties

White to Off-White Solid

Chemical Properties

White crystalline powder. Mp 231-234 deg.] C (decomposition). Odorless. Acetate Betamethasone ([987-24-6]) is also white crystalline powder, melting point 205-208 ℃, slightly soluble in alcohol, ethanol, and very slightly soluble in chloroform or ether, insoluble in water, odorless.

Category

Toxic substances

Brand name

Celestone Syrup and Tablets (Schering).

Uses

glucocorticoid, antiinflammatory

Acute toxicity

Oral-mouse LD50:> 4500 mg/kg

Purification Methods

Betamethasone crystallises from ethyl acetate, and has max at 238nm (log 4.18) in MeOH. The 21-acetate [287-24-6] crystallises from Me2CO/Et2O (charcoal) m 196-201o (205-208o) and has [] D 20 +140o (CHCl3). [Taub et al. J Am Chem Soc 82 4012 1960, Olivetto et al. J Am Chem Soc 80 6688 1958, Beilstein 8 IV 3501.]

Uses

Hormone drugs.It is mainly used for anti-inflammatory and anti-allergic. It is suitable for rheumatoid arthritis and various skin diseases. Betamethasone role is similiar to dexamethasone, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone and it has few side effects.

Flammability and hazard characteristics

Combustible;Its combustion produces toxic fumes of fluoride.

Uses

Betamethasone is a glucocorticoid used as an anti-inflammatory agent.

Uses

anti-inflammatory, immunosuppressive

hormone drugs

Betamethasone, belongs to adrenal corticosteroids, it is a isomer of dexamethasone , and the role of betamethasone is similiar to prednisolone and dexamethasone , it has anti-inflammatory, anti-rheumatic, anti-allergic and suppression of the immune and other pharmacological effects, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone etc. , it can reduce and prevent tissue response to inflammation and eliminate heat, redness and swelling caused by local non-infectious inflammation, thereby reducing the performance of inflammation, anti-inflammatory effect of this product 0.3mg is equal to dexamethasone 0.75mg, prednisone 5mg or 25mg cortisone .
Betamethasone sodium retention effect is a hundred times more than hydrocortisone, in primary adrenal hypofunction, it can be used together with glucocorticoid for replacement therapy ,and it is used for preventing or inhibiting cell-mediated immune response, delaying allergic reactions and reducing the primary immune response expansion ,it is used for low renin and low aldosterone syndrome and autonomic neuropathy induced orthostatic hypotension.
Currently betamethasone is also used for the treatment of active rheumatoid arthritis, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, atopic dermatitis, eczema, neurodermatitis, seborrheic dermatitis, and pruritus and comprehensive treatment of certain infections.
The product is contraindicated in severe psychiatric history, active duodenal ulcer, recent gastrointestinal anastomosis, heavier osteoporosis, overt diabetes, severe hypertension, virus , bacterial, fungal infections which are failed to control by the use of antimicrobial agents , thrombophlebitis, skin infections, such as impetigo, tinea, jock itch and so on.
The above information is edited by the chemicalbook of Tian Ye.

Storage Characteristics

Ventilated, low-temperature ,dry storeroom.

Extinguishing agent

Dry powder , foam, sand, carbon dioxide, water spray.
InChI:InChI=1/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

378-44-9 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
USP (1066009)  Betamethasone  United States Pharmacopeia (USP) Reference Standard 378-44-9 1066009-200MG 4,662.45CNY Detail
Sigma-Aldrich (B1000000)  Betamethasone  European Pharmacopoeia (EP) Reference Standard 378-44-9 B1000000 1,880.19CNY Detail
TCI America (B1837)  Betamethasone  >98.0%(HPLC) 378-44-9 5g 1,230.00CNY Detail
TCI America (B1837)  Betamethasone  >98.0%(HPLC) 378-44-9 1g 410.00CNY Detail

378-44-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name betamethasone

1.2 Other means of identification

Product number -
Other names Bifas

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:378-44-9 SDS

378-44-9Upstream product

Please post your buying leads,so that our qualified suppliers will soon contact you!

*Required Fields