6-N,N-dimethylamino-2,3-naphthalimide: A new environment-sensitive fluorescent probe in δ- and μ-selective opioid peptides

Article abstract of DOI:10.1021/jm060343t

A new environment-sensitive fluorophore, 6-N,N-(dimethylamino)-2,3- naphthalimide (6DMN) was introduced in the o-selective opioid peptide agonist H-Dmt-Tic-Glu-NH2 and in the μ-selective opioid peptide agonist endomorphin-2 (H-Tyr-Pro-Phe-Phe-NH2). Enviro