5-Chloro-2-lithio-1-pentene and Related Reagents. Efficient Methylenecyclohexane Annulation Sequences

Article abstract of DOI:10.1021/jo00197a060

5-Chloro-2-lithio-1-pentene (7), obtained by transmetalation of the (trimethylstannyl)alkene 11, can be converted into the corresponding Grignard and organocopper reagents.Conjugate addition of the latter species to the enones 13-19, followed by ring clos