Tetrahedron p. 1401 - 1408 (1984)
Update date:2022-08-02
Topics:
Posner, Gary H.
Frye, Leah L.
Hulce, Martin
Conjugate additions of many organometallic reagents to 2-(p-anisylsulfinyl)-2-cycloalkenones, 2, proceed with much greater diastereoselectivity than additions to the corresponding 2-(p-tolylsulfinyl)-2-cycloalkenones, 7.Complexation of 2 with zinc dibromide followed by addition of various Grignard reagents lead, after reductive removal of the sulfoxide, to 3-substituted cycloalkanones of higher optical purity than those obtained from 7.Addition of methyltitanium triisopropoxide to 2-(p-anisylsulfinyl)-2-cyclohexenone, 2b, in the absence of zinc dibromide, proceeds with virtually complete asymmetric induction.
View MoreContact:+86-570-4336358
Address:No.87 Building,Tianqian,Sidu Town
Jiangxi Dongbang Pharmaceutical Co., Ltd.
Contact:+86-795-4433603, 4433388
Address:Fengxin Industrial Park, Fengxin County, Jiangxi Province, P.R.C
Changsha Yihai Chemical Technology Co.,ltd
website:http://www.cs-yihai.com/
Contact:0731- 85620465
Address:Room 23005, unit 2, the northern building of Xiangsong international building , NO.259 Shaoshan Road , Changsha , Hunan, China.(mainland)
HANGZHOU FOREWIN PHARMA CO., LTD
Contact:+86-571-89053961
Address:hangzhou
Wuhan Better Organic Technology Inc.
Contact:13307163183
Address:Wuhan Economic&Technology Development Zone, Hubei
Doi:10.1021/op900192m
(2009)Doi:10.1016/j.bmcl.2006.12.057
(2007)Doi:10.1021/acs.molpharmaceut.7b00442
(2017)Doi:10.1021/ol0630548
(2007)Doi:10.1016/j.jorganchem.2006.12.025
(2007)Doi:10.1021/ja011125m
(2001)
