5-Cinnamoyl-6-aminouracil derivatives as novel anticancer agents. Synthesis, biological evaluation, and structure-activity relationships

DOI: 10.1021/jm00382a020

Source and publish data:

Journal of Medicinal Chemistry p. 497 - 502 (1985)

Update date:2022-08-02

Topics:

Authors:

Bernier Bernier

Henichart

Warin Warin

Trentesaux

Jardillier

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00382a020

A biological evaluation in the series of 5-cinnamoyl-6-aminouracils has been undertaken. These compounds have been found to be in an extended planar conformation fitting well with a possible stacking interaction between the nucleic bases of DNA; thus an e

Full text of DOI:10.1021/jm00382a020

Products guided by the article

Product name:1,3-Dimethyl-6-(3-morpholin-4-yl-propylamino)-5-[(E)-(3-phenyl-acryloyl)]-1H-pyrimidine-2,4-dione; hydrochloride

Cas No:93559-47-8

R&D Labs maybe for 93559-47-8

Jinhua City Mingzhu Pharmaceutical Co.,Ltd.

Contact:15857995878 0579-82207761

Address:No.169 Shenze Road, New Area,Jinpan Development Zone, Jinhua
Zhaodu Fine Chemical Plant

Contact:86-310-8067016

Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
Suqian Ruixing Chemical Co., Ltd.

Contact:+86-527-80805666（总机）;84836008(销售)

Address:3 Jingsilu, Zone north, Hubin Xincheng Development Park, Suqian, China
Xinji City Taida Sinopec Co., Ltd.

Contact:0086-311-85341278

Address:No.6, Nanhua Road,Xinji City Road,Hebei Province,China
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd

Contact:(86) 519-88782201 88784080 88785278

Address:Henglin town, changzhou,Jiangsu

Relevant to this article

An Acid Stable Metal-Organic Framework as an Efficient and Recyclable Catalyst for the O?H Insertion Reaction of Carboxylic Acids

Doi:10.1002/cctc.201800597
(2018)
The first example of a diastereoselective thio-Ugi reaction: A new synthetic approach to chiral imidazole derivatives

Doi:10.1021/jo071030o
(2007)
Luminescent, three-coordinate azadipyrromethene complexes of d¹⁰ copper, silver, and gold

Doi:10.1021/ic700776t
(2007)
Effect of Atomic-Scale Differences on the Self-Assembly of Thiophene-based Polycatenars in Liquid Crystalline and Organogel States

Doi:10.1002/chem.201603678
(2016)
SYNTHESIS OF TWO ENANTIOMERIC TETRASUBSTITUTED CYCLOHEXANONES FROM 6-DEOXYHEX-5-ENOPYRANOSIDE DERIVATIVES

Doi:10.1016/S0008-6215(00)90774-2
(1984)
Synthesis and characterization of poly(ε-caprolactone-co-δ- valerolactone) with pendant carboxylic functional groups

Doi:10.1002/cjoc.201190088
(2011)

Article Doi