Organocatalytic domino Michael-aldol reaction of ketones and α,β-unsaturated trifluoromethyl ketones

Article abstract of DOI:10.1055/s-0028-1083255

Pyrrolidine-catalyzed domino Michael-aldol reaction of α,β- unsaturated trifluoromethyl ketones and ketones was achieved under mild conditions; β-hydroxy-β-trifluoromethyl cyclohexanones were obtained in high yields with good diastereoselectivities. Georg