Tetrahedron Letters p. 4837 - 4840 (1984)
Update date:2022-08-02
Topics:
d'Ischia, M.
Privitera, A.
Prota, G.
Evidence is reported that under physiological conditions anthralin (I), an antipsoriatic drug, reacts with cysteine to give an ether-insoluble adduct which was formulated as 1,8-dihydroxy-10-(2-amino-2-carboxyethylthio)-9-anthrone (III) by model studies and unambiguous synthesis.
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(1984)
