COPPER(I)-INDUCED RADICAL CYCLIZATION OF DIETHYL o-(ALLYLOXY)PHENYLMALONATES TO CHROMAN DERIVATIVES

Article abstract of DOI:10.1246/cl.1984.1931

The reaction of o-(allyloxy)bromobenzenes with copper(I) diethyl malonate afforded diethyl o-(allyloxy)phenylmalonates which under the reaction conditions cyclized to give 4,4-bis(ethoxycarbonyl)-3-methylchromans, 4,4-bis(ethoxycarbonyl)-3-methylenechromans, and 3-(3-butenyl)-4,4-bis(ethoxycarbonyl)chromans.