Novel thiazolo[5,4-b]phenothiazine derivatives: Synthesis, structural characterization, and in vitro evaluation of antiproliferative activity against human leukaemia

Article abstract of DOI:10.3390/ijms18071365

The molecular frame of the reported series of new polyheterocyclic compounds was intended to combine the potent phenothiazine and benzothiazole pharmacophoric units. The synthetic strategy applied was based on oxidative cyclization of N-(phenothiazin-3-yl