Heterocyclic Communications p. 73 - 77 (2010)
Update date:2022-08-05
Topics:
Hu, Lang-Xi
Li, De-Jiang
Bis[(3-benzyloxyphenyl)-1,2,4-triazolo[3,4-b]-[1,3,4]thiadiazole derivatives 3 were synthesized in high yields by reaction of 3-benzyloxyphenyl-4-amino-5-mercapto-1,2,4-triazole 1 with dicarboxylic acid 2 in the presence of POCl3 and tetrabutylammonium iodide as catalyst. The preliminary antibacterial tests showed that most of them were effective against S. aureus, E.coli and B.subtilis.
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