Journal of Medicinal Chemistry p. 136 - 139 (1989)
Update date:2022-08-05
Topics:
Yamashita
Takeda
Matsumoto
Unemi
Yasumoto
O-Benzyl and O-ethyl derivatives of 2'-deoxy-5-(trifluoromethyl)uridine (F3Thd) and 2'-deoxy-5-fluorouridine (FUdR) were synthesized. The oral antitumor activity of the compounds against sarcoma 180 in mice was examined. The 5'-O-ethyl (3b), 3'
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