NOVEL NUCLEOSIDE ANALOGUES VIA DIRECT ATTACK OF CARBON NUCLEOPHILES ON NUCLEOSIDES CONTAINING EPOXY-SUGARS

DOI: 10.1016/S0040-4039(00)98477-6

Source and publish data:

Tetrahedron Letters p. 97 - 100 (1985)

Update date:2022-07-31

Topics:

Authors:

Mete, A.

Hobbs, J. B.

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Article abstract of DOI:10.1016/S0040-4039(00)98477-6

Direct ring-opening of the epoxyde ring in 1-(5'-O-tityl-2',3'-anhydro-β-D-lyxofuranosyl) uracil(1) by lithium acetylide or vinylmagnesium bromide/cuprous iodide affords the corresponding 5'-O-trityl-3'-C-substituted-3'-deoxy-ara-uridine species.

Full text of DOI:10.1016/S0040-4039(00)98477-6

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