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The hydroxamic acid derivative of GluA-NHOH showed in vitro
antioxidant, antiradical, and SSAO inhibitory activities. A variety of
hydroxamic acid derivatives have been reported to exhibit biolog-
ical activities towards cardiovascular diseases, Alzheimer’s disease,
and tuberculosis. In future studies, an ageing animal model will be
used to investigate GluA-NHOH.
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Acknowledgements
Liu, Y. H., Huang, W. J., Lu, Y. L., Lee, C. C., Tsai, Y. F., Wu, W. C., et al. (2011).
Semicarbazide-sensitive amine oxidase inhibitory activities of galacturonic acid
hydroxamate. Botanical Studies, 52, 35–40.
Liu, D. Z., Lin, Y. S., & Hou, W. C. (2004). Monohydroxamates of aspartic acid and
glutamic acid exhibit antioxidant and angiotensin converting enzyme
inhibitory activities. Journal of Agricultural and Food Chemistry, 52, 2386–2390.
Liu, Y. H., Lin, S. Y., Lee, C. C., & Hou, W. C. (2008). Antioxidant and nitric oxide
production inhibitory activities of galacturonyl hydroxamic acid. Food
Chemistry, 109, 159–166.
The authors want to thank the financial support (SKH-TMU-
100-07) from Shin Kong Wu Ho-Su Memorial Hospital, Taipei,
Taiwan.
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