Bu2iAlCl - Cp2TiCl2 - A new reagent for hydroalumination of disubstituted acetylenes

Article abstract of DOI:10.1007/BF01431127

A new regio- and stereoselective method for the synthesis of E-alkenylchloralanes based on Cp₂TiCl₂-calalyzed hydroalumination of disubstituted acetylenes by diisobutylaluminum chloride was developed. Hydrolysis and deuterolysis of organoaluminum compounds lead to the corresponding Z-olefins, and cross-coupling with allyl halides in the presence of Pd(Ph₃P)₄ results in the formation of cis-4,5-disubstituted 1,4-dienes.