Bulletin of the Chemical Society of Japan p. 373 - 377 (1995)
Update date:2022-08-11
Topics:
Kusama, Hiroyuki
Yamashita, Yuko
Narasaka, Koichi
The Beckmann rearrangement of oximes is catalyzed by a combined use of tetrabutylammonium perrhenate (Bu4NReO4) and trifluoromethanesulfonic acid in nitromethane under azeotropic conditions, giving amides in high yield.By employing this catalytic system, amides can be prepared directly from ketones and hydroxylamine hydrochloride.
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