Name: Stanozolol
SKU: 10418-03-8

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Basic Information

Molecular Structure:
CAS No.:	10418-03-8
Name:	Stanozolol

Formula:	C₂₁H₃₂N₂O
Molecular Weight:	328.498
Synonyms:	2'H-5a-Androst-2-eno[3,2-c]pyrazol-17b-ol, 17-methyl- (8CI);17-Methyl-5a-androstano[3,2-c]pyrazol-17b-ol;17-Methyl-pyrazolo[4',3':2,3]-5a-androstan-17b-ol;17a-Methyl-17b-hydroxy-5a-androstano(3,2-c)pyrazole;17b-Hydroxy-17-methyl-5a-androstano[3,2-c]pyrazole;Anabol;Androstanazol;Androstanazolestanazol;Estazol;Stanazolol;Stromba;Strombaject;Tevabolin;Win 14833;Winstrol;
EINECS:	233-894-8
Density:	1.129 g/cm³
Melting Point:	242 °C
Boiling Point:	490.8 °C at 760 mmHg
Flash Point:	250.7 °C
Appearance:	white to light yellow powder
Hazard Symbols:	Xn,Xi
Risk Codes:	63
Safety:	53-22-36/37/39-36-26
PSA:	48.91000
LogP:	4.11810

Synthetic route

17β-hydroxy-2-hydroxymethylene-17α-methyl-5α-androstan-3-one: 17β-hydroxy-2-hydroxymethylene-17α-methyl-5α-androstan-3-one

: 10418-03-8
stanozolol

Conditions

Conditions	Yield
With hydrazine

: 10418-03-8
stanozolol

: 7693-46-1
4-Nitrophenyl chloroformate

: tanozolol-4-nitrophenyl-carbonate

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃; for 3h; pH=8.5;	76.85%

: 10418-03-8
stanozolol

: 17,17-dimethyl-18-nor-5α-androst-13(14)-eno<3,2-c>pyrazole

Conditions

Conditions	Yield
With hydrogenchloride for 0.25h; Ambient temperature;	66%

: 10418-03-8
stanozolol

: 124-63-0
methanesulfonyl chloride

: 107000-35-1
(1S,3aS,3bR,5aS,10aS,10bS,12aS)-8-Methanesulfonyl-1,10a,12a-trimethyl-1,2,3,3a,3b,4,5,5a,6,8,10,10a,10b,11,12,12a-hexadecahydro-7,8-diaza-dicyclopenta[a,h]phenanthren-1-ol

Conditions

Conditions	Yield
With pyridine at 0 - 20℃; for 1h;	56%

: 14660-52-7
ethyl 5-bromovalerate

: 10418-03-8
stanozolol

A: ethyl-5-{17β-hydroxy-17α-methylpyrazolo[3′,4′:3,2]-5α-androstan-1′-yl}pentanoate

B: ethyl 5-{17α-methyl-17β-hydroxypyrazolo[4′,5′:2,3]-5α-androstan-1′-yl}pentanoate

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 80℃; for 5h; Microwave irradiation;	A 38% B 28%

...Expand

: 10418-03-8
stanozolol

: 21085-72-3
1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester

A: 2′‑[N‑(methyl 2,3,4‑tri‑O‑acetyl‑1‑deoxy‑β‑d‑glucuronosyluronate)]‑17α‑methyl‑5α‑androstano[3,2‑c]pyrazol‑17β‑ol

B: 1′‑[N‑(methyl 2,3,4‑tri‑O‑acetyl‑1‑deoxy‑β‑d‑glucuronosyluronate)]‑17α‑methyl‑5α‑androstano[3,2‑c]pyrazol‑17β‑ol

Conditions

Conditions	Yield
With mercury(II) cyanide; mercury dibromide In nitromethane; benzene for 3h;	A 17% B 5%

...Expand

: 110-86-1
pyridine

: 10418-03-8
stanozolol

: stanozolol 17β-sulfate pyridinium salt

Conditions

Conditions	Yield
With chlorosulfonic acid 1.) -5 deg C, 2.) RT, 3 h; Yield given. Multistep reaction;

: 10418-03-8
stanozolol

: Sulfuric acid mono-((1S,3aS,3bR,5aS,10aS,10bS,12aS)-1,10a,12a-trimethyl-1,2,3,3a,3b,4,5,5a,6,8,10,10a,10b,11,12,12a-hexadecahydro-7,8-diaza-dicyclopenta[a,h]phenanthren-1-yl) ester

Conditions

Conditions	Yield
With sulfur trioxide pyridine complex In N,N-dimethyl-formamide for 2h; Ambient temperature;

: 10418-03-8
stanozolol

: 145841-85-6, 125636-91-1
17-epistanozolol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sulfur trioxide pyridine complex / dimethylformamide / 2 h / Ambient temperature 2: K2CO3 / dimethylformamide; H2O / 72 h View Scheme

: 2174-58-5
L-malic acid

: 10418-03-8
stanozolol

: ((1S,3aS,3bR,5aS,10aS,10bS,12aS)-1,10a,12a-trimethyl-1,2,3,3a,3b,4,5,5a,6,7,10,10a,10b,11,12,12a-hexadecahydrocyclopenta[5,6]naphtho[1,2-f ]indazol-1-ol)*(S-methylsuccinic acid)

Conditions

Conditions	Yield
In methanol Milling;

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Specification

The systematic name of Stanozolol is (1S,3aS,3bR,5aS,10aS,10bS,12aS)-1,10a,12a-trimethyl-1,2,3,3a,3b,4,5,5a,6,7,10,10a,10b,11,12,12a-hexadecahydrocyclopenta[5,6]naphtho[1,2-f]indazol-1-ol. With the CAS registry number 10418-03-8, it is also named as 17-Methyl-2'H-5alpha-androst-2-eno(3,2-c)pyrazol-17beta-ol. The product's categories are pharmaceutical; active pharmaceutical ingredients; biochemistry; steroids. It is white to light yellow powder which was developed by Winthrop Laboratories in 1962. And it is a synthetic anabolic steroid derived from testosterone, and has been approved by the FDA for human use. But in the United States, like other anabolic steroids, stanozolol is classified as a controlled substance under federal regulation.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 5.53; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 5.52; (4)ACD/LogD (pH 7.4): 5.53; (5)ACD/BCF (pH 5.5): 9063.27; (6)ACD/BCF (pH 7.4): 9432.91; (7)ACD/KOC (pH 5.5): 23400.01; (8)ACD/KOC (pH 7.4): 24354.36; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 1; (12)Index of Refraction: 1.573; (13)Molar Refractivity: 95.87 cm³; (14)Molar Volume: 290.8 cm³; (15)Polarizability: 38×10^-24 cm³; (16)Surface Tension: 48.8 dyne/cm; (17)Enthalpy of Vaporization: 79.77 kJ/mol; (18)Vapour Pressure: 1.89E-10 mmHg at 25°C; (19)Tautomer Count: 2; (20)Exact Mass: 328.251464; (21)MonoIsotopic Mass: 328.251464; (22)Topological Polar Surface Area: 48.9; (23)Heavy Atom Count: 24.

Preparation: The pyrazole ring in stanozolol can be prepared by the condensation of a keto-aldehyde with hydrazine.

Uses of Stanozolol: It is used in chronic wasting disease, weight loss of illness and after surgery, elderly and frail, osteoporosis, stunted children, aplastic anemia and so on. Stanozolol is commonly used by athletes and bodybuilders alike to lose fat while retaining lean body mass. Additionly, it is preferred by many steroid users due to the fact that it causes strength increases without excess weight-gain, promotes increases in vascularity, and will not convert to estrogen.

When you are using this chemical, please be cautious about it as the following:
It is possible risk of harm to the unborn child, so people should not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. Additionally, avoid exposure - obtain special instructions before use.

People can use the following data to convert to the molecule structure.
1. SMILES:O[C@@]5(C)CC[C@H]4[C@H]3[C@@H]([C@]2(Cc1c(nnc1)C[C@@H]2CC3)C)CC[C@@]45C
2. InChI:InChI=1/C21H32N2O/c1-19-11-13-12-22-23-18(13)10-14(19)4-5-15-16(19)6-8-20(2)17(15)7-9-21(20,3)24/h12,14-17,24H,4-11H2,1-3H3,(H,22,23)/t14-,15+,16-,17-,19-,20-,21-/m0/s1

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Specification