Enzyme-catalyzed Lactonization of Methyl (+/-)-(E)-3,5-Dihydroxy-7-phenyl-6-heptenoates. - A Comparison of the Behaviour of syn- and anti-Compounds

DOI: 10.1016/S0957-4166(00)82325-3

Source and publish data:

Tetrahedron Asymmetry p. 153 - 156 (1993)

Update date:2022-08-12

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Authors:

Henkel, Birgitta

Kunath, Annamarie

Schick, Hans

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Article abstract of DOI:10.1016/S0957-4166(00)82325-3

3-Hydroxy lactones with a high enantiomeric excess were obtained by the lipase-catalyzed enantioselective lactonization of racemic syn- and anti-3,5-dihydroxy carboxylic esters.The (5S)-lactones were formed predominantly from both diols with pancreatin as

Full text of DOI:10.1016/S0957-4166(00)82325-3

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Product name:methyl (+/-)-(3R*,5R*,6E)-3,5-dihydroxy-7-phenyl-6-heptanoate

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