Tetrahedron Letters p. 5915 - 5918 (1985)
Update date:2022-08-17
Topics:
Nickon, Alex
Stern, Alfred G.
An efficient, eight-step synthesis of brexan-2-one has been developed (25.5percent overall yield). The strategy also provided two convenient routes to homobrexan-2-one. The schemes can be easily adapted to introduce isotopic labels for mechanistic studies.
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