Theoretical studies, synthesis, and biological activity of 1-[(4-methylphenyl)sulfonyl]-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-4- carbonitrile (C9) as a non-peptide antagonist of the arginine vasopressin V1a and V2 receptors

Article abstract of DOI:10.1007/s00044-013-0739-5

In this work, the synthesis of 1-[(4-methylphenyl)sulfonyl]-5-oxo-2,3,4,5- tetrahydro-1H-1-benzazepine-4-carbonitrile (C9) and the study of its biological activity as a new putative antagonist of vasopressin receptors are described. The chemical identific