NMR Spectra of Dimethyl 1-Acetyl-1,2-dihydro-2-quinolyl-phosphonate and Related Compounds

Article abstract of DOI:10.1246/bcsj.59.2362

1H, 13C, and 31P NMR spectra of the products from the Reissert type reactions using acyl halides and trimethyl phosphite were measured and correlated with their structures. 31P Chemical shift of dimethoxyphosphinyl group and 13C chemical shift of the α-carbon atom, as well as ¹J_CP and ²J_PH can be criteria to differentiate the 1,2- and the 1,4-adducts from each other.Thus, there NMR parameters can be a clue to elucidate the regioselectivity of the reactions.