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2687-91-4

Basic Information
CAS No.: 2687-91-4
Name: 1-Ethyl-2-pyrrolidinone
Molecular Structure:
Molecular Structure of 2687-91-4 (1-Ethyl-2-pyrrolidinone)
Formula: C6H11NO
Molecular Weight: 113.18
Synonyms: 1-Ethyl-2-pyrrolidone;1-Ethylazacyclopentan-2-one;N-Ethyl-a-pyrrolidinone;N-Ethyl-g-butyrolactam;N-Ethylbutyrolactam;N-Ethylpyrrolidone;NEP;NEP 100;1-Ethyl-2-pyrrolidinone;
EINECS: 220-250-6
Density: 0.993 g/cm3
Melting Point: 87.5-88.5 °C
Boiling Point: 203.6 °C at 760 mmHg
Flash Point: 76.1 °C
Solubility:
Appearance: clear liquid
Hazard Symbols: HarmfulXn
Risk Codes: 22-36
Safety: 26-36
Transport Information:
PSA: 20.31000
LogP: 0.56660
Synthetic route
88-12-0

1-ethenyl-2-pyrrolidinone

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
With C7H14N3(1+)*Cl(1-); sodium triethylborohydride; cobalt(II) chloride In tetrahydrofuran at 25℃; under 7500.75 Torr; for 16h;99%
With ammonium formate; palladium on activated charcoal In methanol for 0.5h; Heating;94%
With oxygen; hydrazine hydrate; 7-(trifluoromethyl)-1,10-ethyleneisoalloxazinium chloride In water at 100℃; under 760.051 Torr; for 18h;88%
96-48-0

4-butanolide

75-04-7

ethylamine

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
In water; ethylene glycol at 290℃; under 38787.1 Torr; Kinetics; Temperature; Concentration; Flow reactor;93.9%
at 300℃;
at 215℃;
88-12-0

1-ethenyl-2-pyrrolidinone

25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

A

2687-91-4

1-ethyl-2-pyrrolidinone

B

1190639-19-0

1-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl)pyrrolidin-2-one

Conditions
ConditionsYield
With Rh(acac)(dppb) In tetrahydrofuran for 18h; Inert atmosphere; regioselective reaction;A n/a
B 83%
6112-00-1

N,N-diethyl-2-diazoacetamide

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
dirhodium tetraacetate In dichloromethane at 40℃; for 5h;77%
616-45-5

2-pyrrolidinon

74-96-4

ethyl bromide

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
Stage #1: 2-pyrrolidinon; ethyl bromide With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 2h;
Stage #2: at 0℃;
75%
14468-90-7

N-trimethylsilyl-pyrrolidin-2-one

515-46-8

Ethyl benzenesulfonate

A

2687-91-4

1-ethyl-2-pyrrolidinone

B

17882-06-3

trimethylsilyl benzenesulfonate

Conditions
ConditionsYield
Heating;A 59%
B 72%
96-48-0

4-butanolide

141-43-5

ethanolamine

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
ZSM-569%
96-48-0

4-butanolide

121-44-8

triethylamine

A

2687-91-4

1-ethyl-2-pyrrolidinone

B

64-17-5

ethanol

Conditions
ConditionsYield
ZSM-5A 68%
B 13%
616-45-5

2-pyrrolidinon

74-85-1

ethene

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
With silver tetrafluoroborate; dibromo[1,3-dihydro-1-(2-pyridinyl)-3-(2,4,6-trimethylphenyl)-2H-imidazol-2-ylidene]platinum(II) In nitrobenzene-d5 at 20 - 150℃; under 4125.41 Torr; for 26h; Inert atmosphere;59%
6112-00-1

N,N-diethyl-2-diazoacetamide

A

2687-91-4

1-ethyl-2-pyrrolidinone

B

31366-13-9

1-ethyl-4-methyl-2-azetidinone

C

111328-65-5

C12H22N2O2

Conditions
ConditionsYield
With Cu(1+)*HB(C3N2Br3)3(1-)=(HB(C3N2Br3)3)Cu In dichloromethane at 20℃; Inert atmosphere; chemoselective reaction;A 51%
B 20%
C 17%
With copper(I) hydrotris(3,5-dimethylpyrazol-1-yl)borate In dichloromethane at 20℃; Inert atmosphere; chemoselective reaction;
616-45-5

2-pyrrolidinon

75-03-6

ethyl iodide

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
With sodium hydride Heating;42%
6112-00-1

N,N-diethyl-2-diazoacetamide

A

N1,N1,N4,N4-tetraethylmaleamide

B

2687-91-4

1-ethyl-2-pyrrolidinone

C

111328-65-5, 138895-86-0, 37511-04-9

N1,N1,N4,N4-tetraethylfumaramide

Conditions
ConditionsYield
Ru2(CO)4[(PrO)4-5,17-Br2-11,23-(CO2-)2-calix[4]arene] In dichloromethane at 40℃; for 24h;A 17%
B 23%
C 14%
96-48-0

4-butanolide

121-44-8

triethylamine

A

2687-91-4

1-ethyl-2-pyrrolidinone

B

64-17-5

ethanol

Conditions
ConditionsYield
Conversion of starting material;A n/a
B 13%
2314-78-5

N-ethylsuccinimide

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
With sulfuric acid; water Bei der elektrolytischen Reduktion an einer Blei-Kathode.;
With 5% active carbon-supported ruthenium; hydrogen In water at 150℃; under 112511 Torr; for 6h; Green chemistry;
63867-13-0

4-(N,N-diethylamino)butanoic acid

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
With phosphorus trichloride Erhitzen des Reaktionsprodukts auf 155-160grad.;
854852-25-8

3-hydroxy-4-nitro-butyric acid ethyl ester

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
With 1,4-dioxane; ethanol; copper oxide-chromium oxide at 260℃; under 191232 Torr; Hydrogenation;
67-56-1

methanol

6112-00-1

N,N-diethyl-2-diazoacetamide

A

2687-91-4

1-ethyl-2-pyrrolidinone

B

31366-13-9

1-ethyl-4-methyl-2-azetidinone

C

30280-35-4

N,N-diethylglycine methyl ester

D

70814-00-5

2-methoxy-N,N-diethyl-acetamide

Conditions
ConditionsYield
at 0℃; for 0h; Product distribution; Irradiation; variuos temp.;A 16.8 % Chromat.
B 37.5 % Chromat.
C 11.9 % Chromat.
D n/a
N-acetyl-α-pyrrolidone

N-acetyl-α-pyrrolidone

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
With sulfuric acid at 45℃; elektrolytische Reduktion;
2314-78-5

N-ethylsuccinimide

7664-93-9

sulfuric acid

A

7335-06-0

1-ethylpyrrolidine

B

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
at 28℃; elektrochemischen Reduktion an einer Blei-Kathode;
123-91-1

1,4-dioxane

64-17-5

ethanol

854852-25-8

3-hydroxy-4-nitro-butyric acid ethyl ester

copper oxide-chromium oxide

copper oxide-chromium oxide

A

7335-06-0

1-ethylpyrrolidine

B

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
at 260℃; under 191232 Torr; Hydrogenation;
76572-84-4

4-(ethylamino)butyric acid

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
at 100℃; vom pH 1.2 bis pH 12.7;
76572-84-4

4-(ethylamino)butyric acid

71-36-3

butan-1-ol

A

2687-91-4

1-ethyl-2-pyrrolidinone

B

7732-18-5

water

Conditions
ConditionsYield
at 100℃;
616-45-5

2-pyrrolidinon

C2H5X

C2H5X

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
With sodium hydride at 60 - 70℃;
3445-11-2

1-(2-hydroxyethyl)-2-pyrrolidinone

A

616-45-5

2-pyrrolidinon

B

2687-91-4

1-ethyl-2-pyrrolidinone

C

88-12-0

1-ethenyl-2-pyrrolidinone

Conditions
ConditionsYield
0.37 - 1.6 % cesium on silica In water at 350 - 375℃; for 3 - 95h; Product distribution / selectivity;
0.37 - 1.6 % cesium on silica at 350 - 375℃; for 3 - 95h; Product distribution / selectivity;
88-12-0

1-ethenyl-2-pyrrolidinone

25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

A

2687-91-4

1-ethyl-2-pyrrolidinone

B

1190639-18-9

((CH3)4C2O2)BCHCHNC4H6O

C

1190639-19-0

1-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl)pyrrolidin-2-one

Conditions
ConditionsYield
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)] In benzene-d6 for 18h; Inert atmosphere;
616-45-5

2-pyrrolidinon

64-17-5

ethanol

2687-91-4

1-ethyl-2-pyrrolidinone

Conditions
ConditionsYield
With ammonium bromide at 250℃; for 5h; Autoclave;
1455-13-6

deuteromethanol

6112-00-1

N,N-diethyl-2-diazoacetamide

A

2687-91-4

1-ethyl-2-pyrrolidinone

B

31366-13-9

1-ethyl-4-methyl-2-azetidinone

C

1167575-44-1

C7H14(2)HNO2

Conditions
ConditionsYield
Irradiation;
6112-00-1

N,N-diethyl-2-diazoacetamide

A

2687-91-4

1-ethyl-2-pyrrolidinone

B

31366-13-9

1-ethyl-4-methyl-2-azetidinone

Conditions
ConditionsYield
In chloroform Irradiation;
2687-91-4

1-ethyl-2-pyrrolidinone

407-25-0

trifluoroacetic anhydride

(Z)-3-(1-chloro-2,2,2-trifluoroethylidene)-1-ethylpyrrolidin-2-one

Conditions
ConditionsYield
With aluminum (III) chloride In N,N-dimethyl-formamide at 60℃; for 24h;95%
2687-91-4

1-ethyl-2-pyrrolidinone

2314-78-5

N-ethylsuccinimide

Conditions
ConditionsYield
With ruthenium(IV) oxide; sodium periodate In ethyl acetate for 15h; Ambient temperature;93%
2687-91-4

1-ethyl-2-pyrrolidinone

77-78-1

dimethyl sulfate

C7H14NO(1+)*CH3O4S(1-)

Conditions
ConditionsYield
In neat (no solvent) at 20℃; for 12h; Inert atmosphere;92%
2687-91-4

1-ethyl-2-pyrrolidinone

4083-64-1

Tosyl isocyanate

131657-47-1

(E)-N-(1-ethylpyrrolidin-2-ylidene)-4-methylbenzenesulfonamide

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 18h;91%
2687-91-4

1-ethyl-2-pyrrolidinone

A

N-ethyl-3-phenethylpyrrolidin-2-one

B

N-ethyl-3,3-diphenethylpyrrolidin-2-one

Conditions
ConditionsYield
With potassium tert-butylate at 80℃; for 2h; Sealed tube;A 86%
B 5%
2687-91-4

1-ethyl-2-pyrrolidinone

1-ethylpyrrolidine hydrochloride

Conditions
ConditionsYield
Stage #1: 1-ethyl-2-pyrrolidinone With bis(cyclopentadienyl)dihydrozirconium; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane at 20℃; under 760.051 Torr; for 12h; Inert atmosphere;
Stage #2: With hydrogenchloride In diethyl ether Inert atmosphere;
86%
2687-91-4

1-ethyl-2-pyrrolidinone

1-Ethylpyrrolidine-2-thione

Conditions
ConditionsYield
With Lawessons reagent In tert-butyl methyl ether at 20℃; for 16h; Inert atmosphere;85%
With Lawessons reagent In benzene for 4h; Heating;83%
Multi-step reaction with 2 steps
1: POCl3 / CH2Cl2 / 0.5 h / -78 °C
2: hexamethyldisilathiane / CH2Cl2 / 6 h / Ambient temperature
View Scheme
2687-91-4

1-ethyl-2-pyrrolidinone

614-18-6

3-pyridinecarboxylic acid ethyl ester

1-ethyl-3-nicotinoyl-2-pyrrolidinone

Conditions
ConditionsYield
With sodium hydride In toluene for 48h; Heating;85%
2687-91-4

1-ethyl-2-pyrrolidinone

700-58-3

2-Adamantanone

913335-86-1

2-(1-ethyl-2-oxopyrrolidin-3-yl)tricyclo[3.3.1.13,7]decan-2-ol

Conditions
ConditionsYield
Stage #1: 1-ethyl-2-pyrrolidinone With lithium diisopropyl amide In tetrahydrofuran; diethyl ether; hexane at -80℃; for 0.333333h;
Stage #2: 2-Adamantanone In tetrahydrofuran; diethyl ether; hexane at -80 - 20℃; Further stages.;
84%
Stage #1: 1-ethyl-2-pyrrolidinone With lithium diisopropyl amide at -70℃;
Stage #2: 2-Adamantanone In tetrahydrofuran at -80℃;
2687-91-4

1-ethyl-2-pyrrolidinone

1333433-21-8

(E)-methyl 2-(2-methoxy-3-oxoisoindolin-1-ylidene)acetate

(E)-methyl 2-(1-ethyl-5-oxopyrrolidin-2-yl)-2-(3-oxoisoindolin-1-ylidene)acetate

Conditions
ConditionsYield
With air at 100℃; for 3h; Green chemistry; regioselective reaction;82%
2687-91-4

1-ethyl-2-pyrrolidinone

67217-55-4

mono-6-deoxy-6-(p-tolylsulphonyl)-β-cyclodextrin

6I-O-(N-ethyl-4-aminobutanoyl)cyclomaltoheptaose p-toluenesulfonate

Conditions
ConditionsYield
at 90℃;80%
2687-91-4

1-ethyl-2-pyrrolidinone

1352122-79-2

(E)-methyl 2-(2-methoxy-4-methyl-3-oxoisoindolin-1-ylidene)acetate

(E)-methyl 2-(1-ethyl-5-oxopyrrolidin-2-yl)-2-(4-methyl-3-oxoisoindolin-1-ylidene)acetate

Conditions
ConditionsYield
With air at 100℃; for 12h; Green chemistry; regioselective reaction;79%
2687-91-4

1-ethyl-2-pyrrolidinone

18620-02-5

(4-bromophenyl)magnesium bromide

1109230-92-3

5-(4-bromophenyl)-1-ethyl-2,3-dihydropyrrole

Conditions
ConditionsYield
Stage #1: 1-ethyl-2-pyrrolidinone; (4-bromophenyl)magnesium bromide In diethyl ether at 20℃; Cooling with ice; Inert atmosphere;
Stage #2: With hydrogenchloride; water In diethyl ether pH=3 - 4; Cooling with ice;
Stage #3: With sodium hydroxide In water
78%
2687-91-4

1-ethyl-2-pyrrolidinone

100-58-3

phenylmagnesium bromide

1109230-81-0

1-ethyl-5-phenyl-2,3-dihydropyrrole

Conditions
ConditionsYield
Stage #1: 1-ethyl-2-pyrrolidinone; phenylmagnesium bromide In diethyl ether at 20℃; Cooling with ice; Inert atmosphere;
Stage #2: With hydrogenchloride; water In diethyl ether pH=3 - 4; Cooling with ice;
Stage #3: With sodium hydroxide In water
78%
2687-91-4

1-ethyl-2-pyrrolidinone

39216-86-9

4-(ethylamino)butan-1-ol

Conditions
ConditionsYield
With ethanol; sodium In hexane at 0℃; for 0.333333h; Inert atmosphere; chemoselective reaction;78%
With ethanol; sodium In hexane; paraffin oil at 0℃; for 0.0833333h; Inert atmosphere;22%
2687-91-4

1-ethyl-2-pyrrolidinone

873-77-8

(4-chlorphenyl)magnesium bromide

1109230-91-2

5-(4-chlorophenyl)-1-ethyl-2,3-dihydropyrrole

Conditions
ConditionsYield
Stage #1: 1-ethyl-2-pyrrolidinone; (4-chlorphenyl)magnesium bromide In diethyl ether at 20℃; Cooling with ice; Inert atmosphere;
Stage #2: With hydrogenchloride; water In diethyl ether pH=3 - 4; Cooling with ice;
Stage #3: With sodium hydroxide In water
75%
2687-91-4

1-ethyl-2-pyrrolidinone

100-47-0

benzonitrile

C20H19N3

Conditions
ConditionsYield
With potassium tert-butylate at 110℃; for 16h;74%
2687-91-4

1-ethyl-2-pyrrolidinone

A

2314-78-5

N-ethylsuccinimide

B

932-17-2

N-acetylpyrrolidinone

Conditions
ConditionsYield
With pyridine; N-hydroxyphthalimide; sodium perchlorate In acetonitrile Product distribution; Mechanism; controlled potential electrolysis, electrodes: glassy-carbon vs. SCE;A 73%
B 11%
With pyridine; N-hydroxyphthalimide; sodium perchlorate In acetonitrile controlled potential electrolysis, electrodes: glassy-carbon vs. SCE;A 73%
B 11%
2687-91-4

1-ethyl-2-pyrrolidinone

70-55-3

toluene-4-sulfonamide

131657-47-1

(E)-N-(1-ethylpyrrolidin-2-ylidene)-4-methylbenzenesulfonamide

Conditions
ConditionsYield
With diazoacetic acid ethyl ester; zinc trifluoromethanesulfonate In cyclohexane for 12h; Reflux; stereoselective reaction;73%
2687-91-4

1-ethyl-2-pyrrolidinone

1352122-82-7

(E)-methyl 2-(2,5-dimethoxy-3-oxoisoindolin-1-ylidene)acetate

(E)-methyl 2-(1-ethyl-5-oxopyrrolidin-2-yl)-2-(5-methoxy-3-oxoisoindolin-1-ylidene)acetate

Conditions
ConditionsYield
With air at 100℃; for 12h; Green chemistry; regioselective reaction;72%
2687-91-4

1-ethyl-2-pyrrolidinone

13139-86-1

4-methoxyphenyl magnesium bromide

1109230-89-8

1-ethyl-5-(4-methoxyphenyl)-2,3-dihydropyrrole

Conditions
ConditionsYield
Stage #1: 1-ethyl-2-pyrrolidinone; 4-methoxyphenyl magnesium bromide In diethyl ether at 20℃; Cooling with ice; Inert atmosphere;
Stage #2: With hydrogenchloride; water In diethyl ether pH=3 - 4; Cooling with ice;
Stage #3: With sodium hydroxide In water
71%
2687-91-4

1-ethyl-2-pyrrolidinone

352-13-6

4-flourophenylmagnesium bromide

1109230-90-1

1-ethyl-5-(4-fluorophenyl)-2,3-dihydropyrrole

Conditions
ConditionsYield
Stage #1: 1-ethyl-2-pyrrolidinone; 4-flourophenylmagnesium bromide In diethyl ether at 20℃; Cooling with ice; Inert atmosphere;
Stage #2: With hydrogenchloride; water pH=3 - 4; Cooling with ice;
Stage #3: With sodium hydroxide In water
70%
2687-91-4

1-ethyl-2-pyrrolidinone

229-87-8

phenanthridine

1-ethyl-5-(phenanthridin-6′-yl)pyrrolidin-2-one

Conditions
ConditionsYield
With trifluoroacetic acid; dibenzoyl peroxide In water at 35 - 40℃; for 24h; Inert atmosphere; Irradiation; regioselective reaction;70%
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    ProName:1-Ethyl-2-pyrrolidinone CasNo:2687-91-4 Molecular Formula:C6H11NO Appearance:It is colorless transparent liquid Application:mainly used to produce pharmacy, dye, ... DeliveryTime:7 Days After Get Prepayment PackAg

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    Organic Solvent N-Ethyl-Pyrrolidone/NEP

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    N-Ethyl-Pyrrolidone is a colorless to slightly yellowish liquid with a faint amine odor, as an aprotic and highly polar organic solvent is completely miscible with water .Applications:Used as Intermediates for the synthesis of agrochemicals, pharma

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    N-ETHYL-2-PYRROLIDONE

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

    AFINE CHEMICALS LIMITED is specialized in the fine chemicals and pharmaceuticals and we have enjoyed great popularity in world markets. Since 2005, we have been rapidly growing to

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    Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China

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  • N-Ethyl-2-pyrrolidone

  • Casno:

    2687-91-4

    N-Ethyl-2-pyrrolidone

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

    J&H Chemical is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other

  •  Hangzhou J&H Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-87396432

    Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

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Chemistry

Molecular Formula: C6H11NO
Molecular Weight:  113.16
EINECS: 220-250-6 
Index of Refraction: 1.464
Molar Refractivity: 31.47 cm3
Molar Volume: 113.8 cm3
Surface Tension: 32.6 dyne/cm
Density: 0.993 g/cm3
Flash Point: 76.1 °C
Enthalpy of Vaporization: 43.98 kJ/mol
Boiling Point: 203.6 °C at 760 mmHg
Vapour Pressure: 0.276 mmHg at 25 °C
Appearance: Clear liquid
Structure of 1-Ethyl-2-pyrrolidinone (CAS NO.2687-91-4):
                          
IUPAC Name: 1-Ethylpyrrolidin-2-one
Canonical SMILES: CCN1CCCC1=O
InChI: InChI=1S/C6H11NO/c1-2-7-5-3-4-6(7)8/h2-5H2,1H3
InChIKey: ZFPGARUNNKGOBB-UHFFFAOYSA-N
Product Category of 1-Ethyl-2-pyrrolidinone (CAS NO.2687-91-4): Heterocyclic Building Blocks;Pyrrolidines

Uses

 1-Ethyl-2-pyrrolidinone (CAS NO.2687-91-4) is mainly used in the production of pharmaceuticals, dyestuff, pesticide, etc.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral 1350mg/kg (1350mg/kg) GASTROINTESTINAL: OTHER CHANGES
LIVER: OTHER CHANGES
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Food and Chemical Toxicology. Vol. 26, Pg. 475, 1988.
rat LD50 subcutaneous > 2gm/kg (2000mg/kg)   United States Patent Document. Vol. #4882359,

1-Ethyl-2-pyrrolidinone (CAS NO.2687-91-4) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Moderately toxic by ingestion. An eye irritant. Combustible. When heated to decomposition it emits toxic fumes of NOx.Potential
The Hazard Codes:   Xn
The Risk Statements:
22:  Harmful if swallowed 
26:  Very Toxic by inhalation 
The Safety Statements:
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing 

Specification

 1-Ethyl-2-pyrrolidinone , its cas register number is 2687-91-4. It also can be called N-Ethylpyrrolidinone ; NEP ; and N-Ethyl-2-pyrrolidone . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. Then you have the ingesting of the product: Wash mouth out with water, and get medical aid immediately.
In addition, 1-Ethyl-2-pyrrolidinone (CAS NO.2687-91-4) could be stable under normal temperatures and pressures. It is not compatible with strong oxidizing agents, strong acids, strong bases, acid chlorides, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.