REACTIVITY OF ISOMERIC PYRIDINECARBOXALDEHYDES IN CATALYTIC HYDROGENATION

Article abstract of DOI:10.1007/BF01165032

It has been established by a quantum-chemical method (CNDO/2) that there are two possible mechanisms occuring in the vapor-phase hydrogenation of 2-, 3- and 4-pyridinecarboxaldehydes in the presence of a copper-chromium catalyst at 180-300 deg C.One of these involves a donor-acceptor interaction of aldehyde with catalyst and the addition of hydrogen to the carbon atom of the carbonyl group at the first stage.The second possible mechanism is the synchronous addition of hydrogen to the carbon and oxygen of the carbonyl group of a weakly bound a aldehyde molecule with an unchanged electronic structure.