Tetrahedron p. 1823 - 1826 (1987)
Update date:2022-08-17
Topics:
Cantacuzene, D.
Pascal, F.
Guerreiro, C.
A wide range of N-Boc-amino acid esters were synthesized from N-Boc-amino acids and alcohol using papain as catalyst.Suitable biphasic reaction mixtures were found for most amino acids to achieve high yield of ester synthesis.With N-Boc-L-aspartic and glutamic acids only the α carbonyl group esterified, without racemisation.
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