Acceleration effects of phosphine ligands in the nickel catalyzed methylation of aldehydes using trimethylaluminum

Article abstract of DOI:10.1246/cl.1998.1033

A nickel catalyzed methylation of aldehydes was conducted successfully using trimethylaluminum as an alkylation reagent. In the presence of a phosphine or phosphite ligand, the reaction was considerably accelerated to give the methylation product in good yields.