Organic Letters p. 23 - 25 (2004)
Update date:2022-08-11
Topics:
Zhang, Yingchao
Phillips, Andrew J.
Sammakia, Tarek
(Equation presented) A highly diastereoselective acetate aldol reaction that uses a tert-leucine-derived thiazolidinethione auxiliary and dichlorophenylborane has been developed. The reaction proceeds in excellent yields and with high diastereoselectivities (drs range from 9.5:1 to >100:1).
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