European Journal of Medicinal Chemistry p. 180 - 191 (2017)
Update date:2022-08-11
Topics:
Ge, Ying
Li, Aibo
Wu, Jianwei
Feng, Haiwei
Wang, Letian
Liu, Hongwu
Xu, Yungen
Xu, Qingxiang
Zhao, Li
Li, Yuyan
A novel series of non-peptide proteasome inhibitors bearing the 1, 4-naphthoquinone scaffold and boronic acid warhead was developed. In the biological evaluation on the chymotrypsin-like activity of human 20S proteasome, five compounds showed IC50 View More
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