Journal of Fluorine Chemistry (2020)
Update date:2022-08-17
Topics:
Leppkes, Jakob
Hohmann, Thomas
Koksch, Beate
Fluorine, as a substituent in amino acids, has found its way into peptide and protein engineering. The basis for the use of this valuable tool is the synthetic accessibility of various fluorinated amino acids as building blocks of peptides and proteins. In this context, we present a straightforward eight-step synthesis of N-Fmoc-L-monofluoroethylglycine (MfeGly) via homoserine (Hse) as intermediate and using various nucleophilic fluorination strategies.
View MoreLinHai Cina Chemical Co., LTD.
Contact:0576-85580989
Address:Pharma-chem zone,Duqiao,Linhai,Zhejiang,China
Dalian Synco Chemical Co., Ltd.
Contact:+86-411-83635150
Address:Rm 1004, 24, Tangshan Street, Dalian
Laohekou Jinghong Chemical Co.,Ltd
Contact:+86-0710-3702747
Address:163.East,Huagong Road,Laohekou
SuZhou Hua-Emy Chemical Import and Export Co., LTD.
Contact:+86-512-88804994; +86-512-88804550;
Address:710, Building B, International Trade Center, 12 Huanghelu, Changshu, Jiangsu,China
Huangshi Shennong Chemical Technology Co., Ltd
Contact:+86-714-3072290
Address:Eastern industrial park , Tieshan district , Huangshi city ,Hubei province , China
Doi:10.1002/ejoc.202001165
(2020)Doi:10.1021/ol991139l
(1999)Doi:10.1039/c4ra06870j
(2014)Doi:10.1021/acscatal.7b01486
(2017)Doi:10.1021/jo00929a046
(1974)Doi:10.1002/ejic.201201058
(2013)