Journal of the Chemical Society. Perkin transactions I p. 185 - 187 (1983)
Update date:2022-08-17
Topics:
Grigg, Ronald
Gunaratne, H. Q. Nimal
McNaghten, Edward
The Pictet-Spengler cyclisation of the benzylideneimine of tryptophan methyl ester in xylene, contrary to literature reports, occurs extremely slowly, if at all, in the absence of acids.The cyclisation is Bronsted acid catalysed and the rate of cyclisatio
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