Preparation and characterisation of N-disubstituted 2-amino-4-chloro-5-formyl-thiazoles and their dicyanmethylene derivatives

Article abstract of DOI:10.1002/prac.19963380108

In contrast to N-disubstituted 3-hydroxy-anilines 5 which react with the Vilsmeier reagent to N-substituted 4-amino-salicylaldehydes 7 their heteroanalogous N-disubstituted 2-amino-4-hydroxy-thiazoles 6 react with the same reagent to N-substituted 2-amino