Practical Synthesis of Oligodehydroalanine Derivatives by Repetition of Stepwise Elongation of Serine Derivative and β-Elimination

Article abstract of DOI:10.1246/cl.1994.1301

Facile and practical synthesis of various oligodehydroalanine and its amide derivatives, which compose most of the thiostrepton peptide antibiotics, were first accomplished by repetition of the stepwise elongation of serine derivative and then β-elimination.