Synthetic Communications p. 853 - 861 (2004)
Update date:2022-08-16
Topics:
Ruan, Yuan-Ping
Chen, Ming-De
He, Ming-Zhu
Zhou, Xiang
Huang, Pei-Qiang
A flexible approach to 3-alkyl-2,3-dihydro-1H-isoindolin-1-ones via the reductive-alkylation procedure is described. Present method is versatile in scope, allowing the easy introduction of various C-3 carbon-substituents by Grignard addition to phthalimid
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