Fluoride Ion-Promoted Reaction of Polyfluoro-1-propenyl p-Toluenesulfonate with Amines. Highly Efficient and General Access to (Z)-α-Fluoro-β-amino Acrylaldehydes

Article abstract of DOI:10.1246/cl.1994.1075

2,3,3-Trifluoro-1-propenyl p-toluenesulfonate, readily available by dehydrofluorination of 2,2,3,3-tetrafluoropropyl p-toluenesulfonate, reacted smoothly with various primary or secondary amines in the presence of triethylamine and a catalytic amount of f