Tetrahedron Letters p. 6271 - 6272 (1998)
Update date:2022-08-17
Topics:
Nakanishi, Michael P.
Wu, Weiming
The decarboxylation of 1,3-dimethylorotic acid was investigated to study the nature of the reaction intermediate. 6-Benzyl-1,3-dimethyluracil was isolated when the decarboxylation was carried out in benzyl bromide, indicating the involvement of a carbon-6 centered nucleophilic intermediate in the reaction pathway.
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