39806-38-7

Basic information

• Product Name: 1-Acetyl-5-methyl-2-thioxo-4-imidazolidinone
• Synonyms: 1-Acetyl-5-methyl-2-thioxo-4-imidazolidinone
• CAS NO: 39806-38-7
• Molecular Formula: C₆H₈N₂O₂S
• Molecular Weight: 172.2
• Mol File: 39806-38-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.38
• CAS DataBase Reference: 1-Acetyl-5-methyl-2-thioxo-4-imidazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Acetyl-5-methyl-2-thioxo-4-imidazolidinone(39806-38-7)
• EPA Substance Registry System: 1-Acetyl-5-methyl-2-thioxo-4-imidazolidinone(39806-38-7)

Safety Data

• Hazardous Substances Data: 39806-38-7(Hazardous Substances Data)

Usage

Appearance

White crystalline powder

Usage

Pharmaceutical intermediate

Synthesis

Used in the synthesis of various drugs

Biological activities

Anti-inflammatory
Analgesic
Wound healing
Anti-psoriasis

Additional effects

Antifungal
Antibacterial

Significance

Valuable compound in the field of medicine

Applications

Wide range of applications in the pharmaceutical industry

Upstream product

• 338-69-2 D-Alanine 
• 1147550-11-5 ammonium thiocyanate 
• 302-72-7 rac-Ala-OH 
• 108-24-7 acetic anhydride 
• 1115-69-1 Ac-DL-Ala 
• 56-41-7 L-alanin 
• 333-20-0 potassium thioacyanate 

Downstream Products

• 64143-07-3 1-Acetyl-3,5-dimethyl-2-thioxo-4-imidazolidinon 
• 1068-57-1 acetic acid hydrazide 

Relevant articles and documents

Hydrogen-bonding patterns in rac-1-acetyl-5-methyl-2-thioxoimidazolidin-4- one

In the title compound, C6H8N2O2S, also known as N-acetyl-2-thio-hydantoin- alanine, the mol-ecules are joined by N - H...O hydrogen bonds, forming centrosymmetric R 2 2(8) dimers; these dimers are linked by C - H...O inter-actions to form R 2 2(10) rings, thus forming C 2 2(10) chains that run along the [101] direction. International Union of Crystallography 2007.

New methods for the preparation of aryl 2-iminoimidazolidines

A divergent strategy for the synthesis of 1-aryl- and 2-aryl-2- iminoimidazolidines is presented. Cyclization of N-Boc-N′-aryl-N″- (2-hydroxyethyl)guanidines in the presence of methanesulfonyl chloride and triethylamine or sodium hydride at 0 °C affords the corresponding 2-iminoimidazolidines in good yields.