Stereoselective synthesis of 14,14-difluorocoriolic acid

DOI: 10.1016/0957-4166(94)80051-0

Source and publish data:

Tetrahedron Asymmetry p. 1015 - 1018 (1994)

Update date:2022-08-16

Topics:

Authors:

Kornilov, Andrew M.

Sorochinsky, Alexander E.

Kukhar, Valery P.

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Article abstract of DOI:10.1016/0957-4166(94)80051-0

An efficient, stereoselective synthesis of (R)-14,14-difluoro-13-hydroxy-9(Z),11(E)-octadecadienoic acid ((R)-14,14-difluorocoriolic acid) 2 starting from D-glyceraldehyde acetonide via the key intermediate (R)-3,3-difluoro-1,2-dihydroxyheptane 9 is repor

Full text of DOI:10.1016/0957-4166(94)80051-0

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