A convenient, large scale synthesis of N-CBZ-(S-phenyl)-L-cysteine

Article abstract of DOI:10.1080/00397919508015453

N-Cbz-(S-phenyl)-L-cysteine (3) has been prepared on a multikilogram scale in high yield and optical purity from the β-lactone of N-Cbz-L-serine.

Full text of DOI:10.1080/00397919508015453

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Synthetic Communications: An
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A Convenient, Large Scale Synthesis of
N-CBZ-(S-Phenyl)-L-Cysteine
Gifford Marzoni a , Stephen W. Kaldor b , Anthony J. Trippe a , Brian
M. Shamblin a & James E. Fritz b
a Agouron Pharmaceuticals, Inc. , 3565 General Atomic Court, San
Diego, CA, 92121
b Lilly Research Laboratories, Eli Lilly and Co. , Lilly Corporate
Center, Indianapolis, IN, 46285
Published online: 04 Jan 2007.
To cite this article: Gifford Marzoni , Stephen W. Kaldor , Anthony J. Trippe , Brian M. Shamblin &
James E. Fritz (1995) A Convenient, Large Scale Synthesis of N-CBZ-(S-Phenyl)-L-Cysteine, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry,
25:16, 2475-2482, DOI: 10.1080/00397919508015453
To link to this article: http://dx.doi.org/10.1080/00397919508015453
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