Journal of labelled compounds and radiopharmaceuticals p. 281 - 288 (1995)
Update date:2022-08-31
Topics:
Wassmundt
Kiesman
Aromatic amino groups are replaced with deuterium via a diazonium salt intermediate. Dimethylformamide-d7 is the deuterium donor in this mild replacement method that yields aromatic-d1 products in high isotopic purity. The presence of methyl groups lowers the isotopic purity of the products.
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