Uncatalyzed hydrophosphination of multiple bonds by alkenyl-or alkynyl- phosphine-oxides; evidence for a P-H activation

Article abstract of DOI:10.1016/S0040-4039(97)10755-9

Regiospecific uncatalyzed hydrophosphination of compounds possessing multiple bonds leads to the formation in good yields of various polyfunctionalyzed systems. A good stereoselectivity is observed when a chiral electrophile is used. The mild conditions observed in all these reactions are a consequence of the strong P-H activation induced by the unsaturated fragments directly bonded to the phosphorus atom.