Tetrahedron Letters p. 3567 - 3570 (1995)
Update date:2022-08-28
Topics:
Banks, Malcolm R.
Dawson, Ian M.
Gosney, Ian
Hodgson, Philip K. G.
Thorburn, Paul
(-)-Dihydroprotolichesterinic acid 1a is synthesised in 6 steps and 57percent overall yield by a strategy employing the camphene-derived chiral auxiliary 2 to construct the three contiguous stereogenic centres in consecutive stereocontrolled 1,4-conjugate addition and syn-aldol reactions.
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