Tetrahedron Letters p. 3673 - 3676 (1999)
Update date:2022-08-11
Topics:
Collins, Christopher J.
Lanz, Marc
Singaram, Bakthan
Various 5- and 6-membered tertiary lactams were reduced to the corresponding cyclic tertiary amines using 2.2 to 2.5 equivalents of 9- borabicyclo[3.3.1]nonane (9-BBN). This method is highly chemoselective and it is easy to reduce a lactam in the presence of an ester.
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