Lipase-mediated route to diastereo-pure tranexamic acid

DOI: 10.1248/cpb.43.529

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 529 - 531 (1995)

Update date:2022-08-12

Topics:

Authors:

Watanabe

Hasegawa

Hiroya Hiroya

Ogasawara

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Article abstract of DOI:10.1248/cpb.43.529

Diastereomerically pure tranexamic acid has been prepared via a diastereomeric separation of a trans-/cis-mixture of 1,4-cyclohexanedimethanol using lipase PS (Pseudomonas sp. Amano).

Full text of DOI:10.1248/cpb.43.529

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Product name:1,4-Cyclohexanedimethanol, mono(4-methylbenzenesulfonate), trans-

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