S.A. Patil et al. / Journal of Molecular Structure 985 (2011) 330–338
337
H O
2
H O
2
O
O
N
N
M
M
N
N
O
O
O
O
O
O
H O
2
H O
2
R
R
n
R = H, Br
M = Co(II), Ni(II) and Cu(II)
Fig. 6. Structure of Metal complexes.
[
[
8] S. Kirkiacharian, D.T. Thuy, S. Sicsic, R. Bakhchinian, R. Kurkjian, T. Tonnaire, II
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6
. Conclusion
The new synthesized Schiff bases act as tetradentate. The met-
als are coordinated to azomethine nitrogen, lactonyl oxygen, amide
carbonyl oxygen and phenolic oxygen. The analytical, IR, UV–Vis,
ESR, FAB-mass, magnetic and thermal studies confirm the bonding
of Schiff bases to metal ions. The complexes are soluble in DMF and
DMSO, fusible at higher temperatures and are polymeric in nature.
Electrochemical studies of Cu(II) and Ni(II) complexes exhibited
the one electron transfer quasi-reversible redox couple. The Schiff
bases and their metal complexes were found to be highly active
against some of the bacterial and fungal species. The activity is sig-
nificantly increased on coordination. The DNA cleavage studies re-
vealed that the complexes show non-specific cleavage of DNA.
All these observations put together lead us to propose the struc-
ture shown in Fig. 6.
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Acknowledgements
(
The authors are grateful to the Chairman, Department of Chem-
istry, Karnatak University, Dharwad for the facilities. One of the
authors, S. N. Unki is thankful to Karnatak University, Dharwad
for grant of Research Fellowship in Science for Meritorious
Students of UGC.
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