Synthesis of β-lactams and cyclo-β-dipeptides from β-amino acids: Experimental observations and theoretical analysis

Article abstract of DOI:10.1016/S0040-4020(00)01169-8

The cyclization of β-amino acids by means of activating agents is one of the most useful approaches for the construction of β-lactams; however, we found that when PhP(O)Cl₂ (in Et₃N) is employed as the activating agent, cyclization o