New efficient and stereoselective [2+2] cycloadditions of dimethylaluminum enolates with phenylvinylsulfoxide

Article abstract of DOI:10.1016/S0040-4039(97)01212-4

Lewis-acidic enolates, such as dimethylauminum enolates undergo cis-stereoselective [2+2] cycloadditions with phenylvinylsulfoxide. The method is quite general and gives good yields of synthetically valuable substituted cyclobutanols. The remaining sulfoxide handle can be further manipulated, giving access to diverse chemical functionalities.