Synthesis and properties of oligoribonucleotide analogues having amide (3'-CH2-CO-NH-5') internucleoside linkages

Article abstract of DOI:10.1080/07328319708006117

Amide linked ribonucleoside dimer 5 was prepared and converted into selectively protected H-phosphonate building block 9. Oligoribonucleotide duplexes having amide linkages at selected sites were synthesized and their stability was studied by UV melting e

Full text of DOI:10.1080/07328319708006117

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Nucleosides and Nucleotides
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Synthesis and Properties of
Oligoribonucleotide Analogues
Having Amide (3″-CH2-CO-NH-5′)
Internucleoside Linkages
Eriks Rozners a b & Roger Strömberg a b
a Department of Organic Chemistry , Arrhenius Laboratory,
Stockholm University , S-10691, Stockholm
b Laboratory of Organic and Bioorganic Chemistry, Department
of Medical Biochemistry and Biophysics , Karolinska Institutet ,
S-171 77, Stockholm, Sweden
Published online: 16 Aug 2006.
To cite this article: Eriks Rozners & Roger Strömberg (1997) Synthesis and Properties of
Oligoribonucleotide Analogues Having Amide (3″-CH2-CO-NH-5′) Internucleoside Linkages,
Nucleosides and Nucleotides, 16:7-9, 967-970, DOI: 10.1080/07328319708006117
To link to this article: http://dx.doi.org/10.1080/07328319708006117
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